Replacing objectively measured sedentary time with physical activity: Cross-sectional associations with cardiometabolic risk factors in Japanese employees
ISPAH ePoster Library. Kitano N. 10/15/18; 225324; 140
Dr. Naruki Kitano
Dr. Naruki Kitano
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Abstract
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Abstract Introduction:<\b>
Growing evidence indicates associations between substituting time of sedentary behaviors (SB) with equal time of physical activity (PA) and cardiometabolic risk factors (CmRFs). However, evidence on Japanese subjects who spend long durations in sedentary conditions is limited. We aimed to investigate the effect of reallocating time from SB to low-intensity PA (LPA) or moderate-to-vigorous PA (MVPA) with CmRFs in Japanese employees. Methods:<\b>
Study participants were 1,184 Japanese employees (52.1±9.6 years; 72.1% women) from the 2017 Meiji Yasuda Lifestyle study who underwent annual health checkups for measuring CmRFs. Participants were instructed to wear an accelerometer for 10 days. Time spent in SB (≦1.5 METs), LPA (1.6-2.9 METs), and MVPA (≧3.0 METs) were evaluated. Days with ≧10 h of wear time were considered valid; participants with more than two valid weekdays and one weekend were included. Results:<\b>
Independent of potential confounders, isotemporal substitution modeling indicated that reallocating 30 min/day of SB into an equal duration of MVPA was associated with significantly more favorable waist circumstance (B=-1.17), HDL-c (B=2.74), triglycerides (B=-9.84), and fasting glucose (B=-1.21), and was significantly related with lower prevalence of metabolic syndrome (OR=0.75). In contrast, reallocating 30 min/day of SB into LPA was associated with significantly more detrimental LDL-c (B=1.66) and triglyceride (B=2.67). Conclusion:<\b>
The interrelationships between SB and PA concerning CmRFs would differ by PA intensity; replacing SB with MVPA seems to be effective in Japanese employees. Future studies using bouted/sporadic LPA are warranted to examine its associations with CmRFs.                         
Abstract Introduction:<\b>
Growing evidence indicates associations between substituting time of sedentary behaviors (SB) with equal time of physical activity (PA) and cardiometabolic risk factors (CmRFs). However, evidence on Japanese subjects who spend long durations in sedentary conditions is limited. We aimed to investigate the effect of reallocating time from SB to low-intensity PA (LPA) or moderate-to-vigorous PA (MVPA) with CmRFs in Japanese employees. Methods:<\b>
Study participants were 1,184 Japanese employees (52.1±9.6 years; 72.1% women) from the 2017 Meiji Yasuda Lifestyle study who underwent annual health checkups for measuring CmRFs. Participants were instructed to wear an accelerometer for 10 days. Time spent in SB (≦1.5 METs), LPA (1.6-2.9 METs), and MVPA (≧3.0 METs) were evaluated. Days with ≧10 h of wear time were considered valid; participants with more than two valid weekdays and one weekend were included. Results:<\b>
Independent of potential confounders, isotemporal substitution modeling indicated that reallocating 30 min/day of SB into an equal duration of MVPA was associated with significantly more favorable waist circumstance (B=-1.17), HDL-c (B=2.74), triglycerides (B=-9.84), and fasting glucose (B=-1.21), and was significantly related with lower prevalence of metabolic syndrome (OR=0.75). In contrast, reallocating 30 min/day of SB into LPA was associated with significantly more detrimental LDL-c (B=1.66) and triglyceride (B=2.67). Conclusion:<\b>
The interrelationships between SB and PA concerning CmRFs would differ by PA intensity; replacing SB with MVPA seems to be effective in Japanese employees. Future studies using bouted/sporadic LPA are warranted to examine its associations with CmRFs.                         
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