Understanding the role of physical activity in socio-economic health differences: The active worker individual participant meta-analysis
ISPAH ePoster Library. Coenen P. 10/16/18; 225352; 155
Dr. Pieter Coenen
Dr. Pieter Coenen
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Abstract
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Abstract Introduction:<\b>
A growing body of evidence suggests that workers with high levels of occupational physical activity (OPA), compared to those without, have an increased risk of adverse health outcomes. This adds to the fact that these workers are rather physically inactive during leisure-time. Physical activity (both OPA and LTPA) may therefore play an important role in socio-economic health differences, which we aim to explore in the Active Worker study, an individual participant data meta-analysis. Methods:<\b>
In a review on the relation between OPA and mortality (both cardiovascular and all-cause), while taking LTPA into account, we have identified 24 studies (with n=288,264 participants) with relevant data. PIs of these studies will be invited to the Active Worker consortium, which includes sharing of data and ideas, and manuscript preparation. After merging and harmonizing available data, we will perform regression analyses testing the combined association of OPA and LTPA with mortality outcomes. We will also study the contribution of OPA and LTPA on socio-economic health differences by mediation analysis performing the product-of-coefficients test, as described by MacKinnon. Conclusion:<\b>
Results from the Active Worker study will provide useful information regarding the potentially opposing health effects of OPA and LTPA and their mediating role in socio-economic health differences. Such information can be used to inform physical activity interventions aimed at minimizing socio-economic health differences between workers in different socio-economic strata. External funding details This study has been funded by The Netherlands Organisation for Health Research and Development; ZonMw (grant #: 531-00141-3).
Abstract Introduction:<\b>
A growing body of evidence suggests that workers with high levels of occupational physical activity (OPA), compared to those without, have an increased risk of adverse health outcomes. This adds to the fact that these workers are rather physically inactive during leisure-time. Physical activity (both OPA and LTPA) may therefore play an important role in socio-economic health differences, which we aim to explore in the Active Worker study, an individual participant data meta-analysis. Methods:<\b>
In a review on the relation between OPA and mortality (both cardiovascular and all-cause), while taking LTPA into account, we have identified 24 studies (with n=288,264 participants) with relevant data. PIs of these studies will be invited to the Active Worker consortium, which includes sharing of data and ideas, and manuscript preparation. After merging and harmonizing available data, we will perform regression analyses testing the combined association of OPA and LTPA with mortality outcomes. We will also study the contribution of OPA and LTPA on socio-economic health differences by mediation analysis performing the product-of-coefficients test, as described by MacKinnon. Conclusion:<\b>
Results from the Active Worker study will provide useful information regarding the potentially opposing health effects of OPA and LTPA and their mediating role in socio-economic health differences. Such information can be used to inform physical activity interventions aimed at minimizing socio-economic health differences between workers in different socio-economic strata. External funding details This study has been funded by The Netherlands Organisation for Health Research and Development; ZonMw (grant #: 531-00141-3).
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