Objectively assessed moderate-to-vigorous physical activity is strongly associated with cardiovascular disease after 15 years
ISPAH ePoster Library. Dohrn I. Oct 16, 2018; 225434; 124
Dr. Ing-Mari Dohrn
Dr. Ing-Mari Dohrn
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Abstract Introduction:<\b>
We investigated associations of objectively assessed physical activity (PA) and sedentary time with morbidity in a nationally representative sample with 15-years follow-up. . Methods:<\b>
Data from 1221 women and men, 18-75 years, from the population-based Sweden Attitude Behaviour and Change study were included. Exposure variables were tertiles of daily time spent sedentary, in light intensity PA and in moderate-to-vigorous PA (MVPA), and total counts from an Actigraph 7164 accelerometer. Data on diagnosed cardiovascular disease (CVD), cancer, type-2 diabetes, obesity, depression, dementia, and stroke were obtained from the National Patient Register, which includes all in-patient and out-patient care in Swedish hospitals. Kaplan-Meier survival curves and Cox proportional hazards models estimating hazard ratios (HR) with 95% confidence intervals were used for analyses. Results:<\b>
Over 14.2 years follow-up, 425 persons were diagnosed with at least one of the diseases. Kaplan-Meier analyses showed lower morbidity for CVD, cancer, obesity, dementia, and total morbidity for those in the highest tertile of MVPA compared with the lowest tertile; and lower morbidity for CVD, cancer, type-2 diabetes, and obesity in the highest tertile of total counts compared with the lowest tertile (p<0.05). Those in the highest MVPA tertile had a HR=0.51 (0.32, 0.82) for CVD, HR=0.88 (0.58, 1.33) for cancer, and HR=0.63 (0.48, 0.82) for total morbidity compared with those in the lowest tertile. A similar pattern was found for total counts. No associations were found between morbidity and light intensity PA or sedentary time. Conclusion:<\b>
This study confirms the importance of MVPA for preventing chronic disease. External funding details The original ABC study was funded by Stockholm County Council, Swedish National Centre for Research in Sports, and the project ALPHA, European Union Public Health Programme (agreement 2006120). This study was funded by Folksam Insurance, Sweden.
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