U.S. Physical Activity Guidelines Advisory Committee 2018: Cancer Prevention & Survival
ISPAH ePoster Library. Friedenreich C. Oct 15, 2018; 225570; 154
Dr. Christine Friedenreich
Dr. Christine Friedenreich
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Abstract
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Abstract According to the International Agency for Research on Cancer, there were 14.1 million new cancer cases and 8.2 million cancer deaths in 2012.The 2018 U.S. Physical Activity Guidelines Advisory Committee investigated associations between physical activity and risk for several types of cancer, as well as prognosis among cancer survivors. The Committee considered epidemiologic research conducted through 2016, and primarily relied on systematic reviews, meta-analyses, and pooled analyses of cohort and case-control studies. The Committee found strong evidence that high levels of physical activity reduce risk for bladder, breast, colon, endometrium, esophagus (adenocarcinoma), renal, and gastric cancers, with risk reductions ranging from approximately 10 percent to 20 percent. The Committee’s review of the literature on sedentary behavior and risk of endometrial, colon, and lung cancers found that highest versus lowest levels of sedentary time increased risks of these cancers by a range of 20 percent to 35 percent. The Committee further found inverse association between greater amounts of physical activity and decreased all-cause and cancer-specific mortality in individuals with a diagnosis of breast, colorectal, or prostate cancer, with risk reductions ranging from 38 to 48 percent. The Committee identified several needs for future research, including studies in diverse populations, studies to determine dose-response effects, and randomized controlled trials. This presentation will include the methodology used, the results obtained, and implications for the public and for cancer survivors.
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